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BIO-OPTICS WORLD, May 2008 ARTICLESBio-Optics World is a bi-monthly magazine that provides news, analysis and explanation of applications involving lasers, optics and imaging systems in the life sciences. The magazine is dedicated to giving readers a firsthand look at cutting-edge research related to the design, development and utilization of optical technologies in the study, diagnosis and treatment of disease and disease processes. Bio-Optics World is available by FREE subscription as an electronic (PDF) download. Subscribers must log in to download electronic issues. Table of ContentsFeaturesOptics & ImagingMicroscopes incorporating CMO design are smaller, lighter, more robust, and more reliable.
Combing through the 2009 federal science budget, few bright spots emerge. One plus is the National Science Foundation’s Engineering Directorate, slated to receive $759 million, a 19% increase over FY2008.
Feature FocusTerahertz, Raman, and LIBS offer faster and more accurate nondestructive testing in drug development.
High-throughput spatial accuracy can yield superior intraoperative dynamic range.
More-compact and robust instrumentation has dramatically improved nondestructive identification of drugs in the lab and in the field.
MicroscopyCould adaptive optics be the next big advance in microscope design?
DepartmentsBioOptics BreakthroughsThe latest reseach and technology developments
News & ViewsConventional images of biomolecules, cellular components, and similar targets come with two severe drawbacks: they exist in two dimensions and at a single point in time.
Research fellow Fernanda Sakamoto, MD, of Harvard Medical School and her colleagues at the Wellman Center for Photomedicine at Massachusetts General Hospital (Boston) are using a tunable free-electron laser (FEL) to study the principles of selective photothermolysis as a means of exciting vibrational modes of chemical bond of acne sebum molecules and thus developing more effective laser- and light-based acne treatments.
Engineers and biologists in the Ultrafast Optics and Nanophotonics Laboratory at the University of Alberta (Edmonton, Canada) have demonstrated the advantages of using femtosecond lasers to manipulate molecules and cellular material inside living cells.
In February 2008, the publishers of BioOptics World and Laser Focus World magazines published the first market research report to quantify the rapidly growing market for optical coherence tomography (OCT) technologies and applications.
A team at the optics firm Lasertechnik Berlin (LTB; Berlin, Germany) has developed a laser-based method of identifying the disease.
What began as a relatively simple class project in Prof. Dan Fletcher’s undergraduate optics and microscopy course at the University of California at Berkeley has resulted in the development of a handheld microscopic imaging and transmission device that may have implications for healthcare in Third World, rural, and other underserved communities.
PioneersJoe Lakowicz has always been a bit of a dichotomy. He is a pragmatist at heart; when posed with a problem or a challenge, he starts with the fundamentals, wanting to figure out what makes things tick.
End ResultA microfabricated capillary electrophoresis instrument originally developed by researchers at the University of California, Berkeley, to look for organic molecules on future explorations of Mars could become a fast, inexpensive, portable testing device that helps millions of people avoid headaches following consumption of certain red wines, cheese, chocolate, and other aged or fermented foods.
ColumnsEditorialIn 1978, when my mother was first diagnosed with breast cancer, her options were limited.
In the LoopWhen President George W. Bush unveiled his $3.1 trillion federal budget for fiscal year 2009, biomedical research advocates were hoping this year might be the year of the “bump”—a cost-of-living increase for research.
Inside InstrumentationMy eyes sweep across a lab rat and I can see everything. Images zoom in and out just because my brain starts thinking of looking at different scales.
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